With increasing habitat fragmentation, climate change, and global transport, there are new and increasing threats from pests and pathogens. Our lab is using methods from population genetics, physiology and landscape ecology to investigate several systems: a forest-pest system (mountain pine beetle and hosts), a mosquito arbovirus system (focus on California serogroup viruses), and a mammalian prion disease (chronic wasting disease). This work is to better understand genetic and landscape factors that may contribute to success and movement of pests/pathogens, and determine whether we can identify signals of selection.